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Case Study NeoplasmsCase Study NeoplasmsCase Study: Disorders of Musculoskeleta ...

Case Study Neoplasms

Case Study Neoplasms

Case Study: Disorders of Musculoskeletal Function: Trauma, Infection, Neoplasms

Marvin is a healthy, active 36-year-old who belongs to a martial arts club. Once a week he takes lessons in Judo, and on the weekends, he participates in local competitions. At his last competition, Marvin was paired with a skilled participant from another club.

His rival threw him to the mats, and as Marvin struggled, came down hard to pin him down. Marvin heard a snap, followed by instant pain in his left forearm Case Study Neoplasms. Radiographs at the local hospital confirmed he suffered a transverse fracture of the distal aspect of his left ulna.

  1. What are the typical signs and symptoms of a fracture? Why shortly after the injury does the pain temporarily subside?
  2. How does a hematoma form, and what function does it serve in the process of healing a fracture?
  3. Marvin was told he would be seeing a physiotherapist as his healing progressed. What are the muscular and joint changes that occur during immobilization and the ways Marvin and his physiotherapist can work to address these changes?

Cancer is a neoplasm that can grow rapidly, spread, and cause damage to the body. A malignant neoplasm is cancerous, while a metastatic neoplasm is malignantcancer that has spread to nearby or distant areas of the body.

The cause of benign neoplasm is often not known, but factors such as exposure to radiation or environmental toxins; genetics; diet; stress; inflammation; infection and local trauma or injury may be linked to the formation of these growths.

The sooner a malignant neoplasm is detected, the more effectively it can be treated, so early diagnosis is important. Many types of cancer can be cured. Treatment for other types can allow people to live for many years with cancer.


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Cause and effect relationship in response to diseaseCause and effect relationshi ...

Cause and effect relationship in response to disease

Cause and effect relationship in response to disease

Apply knowledge of tissue and organ structure and function to physiologic alterations in systems and analyze the cause-and-effect relationship.

Select one of the case studies below. In your discussion be sure to include evidence of your knowledge of tissue and organ structure and function to physiologic alterations in systems and analyze the cause-and-effect relationship in response to disease.

Requirements

Make sure all of the topics in the case study have been addressed.

Cite at least three sources—journal articles, textbooks, or evidenced-based websites—to support the content.

All sources must have been written within five years (2012-2017).

Do not use .com, Wikipedia, or up-to-date, etc., for your sources.

Case Study 1

Mechanisms of Infectious Disease

Thirty-two–year-old Jason is a general laborer, who fell ill shortly after working on a job digging up old water pipes for the town he lived in. The task involved working around shallow pools of stagnant water. Ten days after the contract ended, Jason developed a fever and aching muscles.

He also had nausea, vomiting, and diarrhea. Jason’s friend took him to his physician who listened carefully to Jason’s history. She told him she suspected West Nile fever and ordered serological testing. Jason went home to recover and was feeling better by the end of the week.

ORDER THROUGH BOUTESSAY

Jason’s physician ordered serological tests. How would antibody titers assist the doctor in confirming his diagnosis?

When Jason was feeling at his worst, he had extreme malaise, vomiting, and diarrhea. What stage of the illness was he experiencing at that time? What are the physiological mechanisms that give rise to the signs and symptoms of infectious illness?

West Nile virus has a single-stranded RNA genome. How does this virus replicate? In general terms, what are the various effects viruses can have on host cells?

Case Study 2

Innate and Adaptive Immunity

Melissa is a 15-year-old high school student. Over the last week, she had been feeling tired and found it difficult to stay awake in class. By the time the weekend had arrived, she developed a sore throat that made it difficult to eat and even drink.

Melissa was too tired to get out of bed, and she said her head ached. On Monday morning, her mother took her to her doctor. Upon completing the physical exam, he told Melissa the lymph nodes were enlarged in her neck and she had a fever.

He ordered blood tests and told Melissa he thought she had mononucleosis, a viral infection requiring much bed rest.

Innate and adaptive immune defenses work collectively in destroying invasive microorganisms. What is the interaction between macrophages and T lymphocytes during the presentation of antigen?

Melissa’s illness is caused by a virus. Where are type I interferons produced, and why are they important in combating viral infections?

Humoral immunity involves the activation of B lymphocytes and production of antibodies. What are the general mechanisms of action that make antibodies a key component of an immune response?

Case Study 3

Disorders of the Immune Response

Ahmed has worked as a phlebotomist in the local hospital for the last 7 years. Last year, he began to complain of watery, nasal congestion and wheezing whenever he went to work. He suspected he was allergic to something at the hospital because his symptoms abated when he was at home over the weekends.

One day he arrived at work for the morning shift and put on his gloves. Within minutes, he went into severe respiratory distress requiring treatment in the emergency ward. It was determined at that time his allergic response was due to latex exposure.

Ahmed experienced a type I, IgE-mediated hypersensitivity response. How can this be determined by his signs and symptoms? How might another type of latex hypersensitivity reaction present?

How do T2H cells, mast cells, and eosinophils function to produce the signs and symptoms typical of a type I hypersensitivity disorder?

How is it that someone who does not come into direct contact with latex can still have a hypersensitivity response to the material? What do food allergies have to do with latex allergies?

Case Study 4

Inflammation, Tissue Repair, and Wound Healing

Carlton, a six-year-old boy, was playing on a sandy beach with his mother. He began to run along the shoreline when he stepped on the sharp edge of a shell, giving himself a deep cut on his foot. His mother washed his foot in the lake and put on his running shoe to take him home.

One day later, Carlton’s foot looked worse. The gash was red and painful. The foot was warm to touch and appeared swollen. Carlton’s mom put some gauze over the wound and prepared to take him to the local community health clinic.

What is the physiologic mechanism causing the wound to become red, hot, swollen, and painful? How is this different than the inflammatory response that might occur in an internal organ?

What are the immunologic events that are happening at the local level during Carlton’s acute inflammatory response?

Nutrition plays an important factor in wound healing. What stages of wound healing would be affected by a deficiency in vitamins A and C?

Case Study 5

Acquired Immunodeficiency Syndrome

Patience is 29 years old and has been HIV positive for nine years. She has remained asymptomatic and is not taking antiretroviral medication. Recently she was at the drop-in clinic to talk to a public health nurse about having a baby through artificial insemination.

She said she had met a man who wanted to marry her and have children with her, but she was concerned about the baby contracting HIV.

Her latest blood tests indicated her CD4+ count was 380/µL. The PCR test indicated her viral load was 850. The nurse referred her to the physician to discuss antiretroviral therapy during her pregnancy.

What are the factors that increase the chance of HIV transmission from mother to infant, and how the transmission occurs?

Patience was told that after she became pregnant, she would begin HAART therapy. Describe what this therapy is and what particular antiretroviral medication would be particularly useful to her during her pregnancy. What concern is there about administering certain antiretrovirals early in the pregnancy?

Individuals with HIV are prone to contracting opportunistic infections. What are opportunistic infections and the risk factors that leave an individual with HIV particularly prone to contracting this type of illness?

Case Study 6

Blood Cells and the Hematopoietic System

Charlie is a 53-year-old man with non-Hodgkin lymphoma. His treatment has been only modestly successful in delaying the progression of the disease, and he has recently relapsed. His medical team decided to administer aggressive chemotherapy.

Knowing that the intensive treatment would have a destructive effect on Charlie’s bone marrow, they removed stem cells from his blood before the chemotherapy began. Afterward, the stem cells were returned by IV to reestablish his bone marrow function.

What are the therapeutic advantages of an autologous stem cell transplant on Charlie’s bone marrow and immune system?

Before harvesting stem cells, a cytokine growth factor is administered to the patient. What is the benefit of this procedure?

Non-Hodgkin lymphoma is a disease involving B and T lymphocytes. What aspects of the immune response are these cells responsible for?

When considering erythrocytes, how is the body able to meet hematopoietic demand in conditions such as hemolytic anemia or blood loss?


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Case Study: The Case of Goodwill Impairment at Jackson EnterprisesCase Study: Th ...

Case Study: The Case of Goodwill Impairment at Jackson Enterprises

Case Study: The Case of Goodwill Impairment at Jackson Enterprises

Case Study: The Case of Goodwill Impairment at Jackson Enterprises

WRITING ASSESSMENT

By: Casey McNellis, Ronald Premuroso, & Robert Houmes

This writing assessment is designed to enhance your research skills using the FASB Codification and improve your graduate level writing skills. Login credentials to the FASB Codification are provided in the syllabus under Class Guidelines. Case Study: The Case of Goodwill Impairment at Jackson Enterprises

ORDER COMPREHESIVE SOLUTION PAPERS

Academic writing is different from general writing. You are strongly advised to start this project early in the semester and engage the help of UMUC Writing Tutors. Every graduate accounting course offers free UMUC writing tutors Case Study: The Case of Goodwill Impairment at Jackson Enterprises.

Register for a writing tutor at the beginning of the semester and submit drafts of this assignment for guidance Case Study: The Case of Goodwill Impairment at Jackson Enterprises.

Upon receiving guidance from a UMUC writing tutor, improve your next draft, and resubmit your paper for additional guidance. Writing is an iterative process whereby you plan, research, write, edit, research more if needed, rewrite, edit, and rewrite until you have created a clear, concise, and correct paper Case Study: The Case of Goodwill Impairment at Jackson Enterprises.

Instructions:

  • Read the case study and prepare answers to the questions at the end of the case.
  • APA style formatting is required..
  • Approximate length of paper using APA style is 10 pages.

Case Study: The Case of Goodwill Impairment at Jackson Enterprises Resources

Writing a Research Paper: https://owl.english.purdue.edu/owl/resource/658/01/

APA: https://owl.english.purdue.edu/owl/section/2/10/

Developing your graduate level writing skills: https://owl.english.purdue.edu/owl/section/1/2/

Proposed Accounting Standards Update: Simplifying the Accounting for Goodwill Impairment, by FASB; May 12, 2016: http://www.fasb.org/jsp/FASB/Document_C/DocumentPage?cid=1176168146260&acceptedDisclaimer=true

What Constitutes Graduate Level Writing; source unknown. In LEO, Content, Week 9.

1. Identify and cite the relevant topics/subtopics from the FASB Accounting Standards Codification for this case.

Average cost is $1,495; times 1.5385 equals a selling price of $2,300. The $2,300 unit selling price less $1,495 unit cost equals a gross margin of $805, which is 35 percent of selling price.

2. Identify the specific accounting issue that you believe needs to be initially addressed for JE’s consideration of goodwill with regards to both Dynamic and ZD.

3. What does the qualitative evidence from the case indicate about whether JE should perform the two-step impairment test? In your response, identify specific factors discussed in the Codification and relate them to the information provided to you in the case Case Study: The Case of Goodwill Impairment at Jackson Enterprises.

4. Beyond the assessment of qualitative factors, what other evidence should be considered for the purposes of the analysis? What does this information suggest? With respect to Dynamic, what do you think is the most appropriate fair value amount to use in assessing the fair value of this reporting unit? Explain. Why is this important?

5. Based upon the information provided above, should Dynamic and ZD be combined or separated for the purposes of the goodwill analysis? Explain. Why is this important?

6. Based upon your initial analysis, do you think the $200 million goodwill balance (i.e., the $150 million for Dynamic and the $50 million for ZD) is the appropriate valuation for goodwill on the December 31, 2014 balance sheet of JE?

7. Prepare a memo detailing the issues involved, the judgments you made in connection with the authoritative literature, and your recommendation for the direction of the goodwill valuation as it relates to Dynamic and ZD (i.e., does the evidence suggest further action is required in determining the appropriate valuation of goodwill? If so, what steps need to be taken?). Case Study: The Case of Goodwill Impairment at Jackson Enterprises


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Chamberlain NR451 Capstone Project PaperNR451 Capstone ProjectDirections: Please ...

Chamberlain NR451 Capstone Project Paper

NR451 Capstone Project

Directions: Please choose ONE topic and its corresponding systematic review that is of most interest to you, or most relevant to your practice Chamberlain NR451 Capstone Project Paper. This systematic review will be the basis for your capstone project. Please refer to the guidelines for each milestone for more details.

Promoting breastfeeding

Sinha, B., Chowdhury, R., Sankar, M. J., Martines, J., Taneja, S., Mazumder, S., … Bhandari, N. (2015). Interventions to improve breastfeeding outcomes: A systematic review and meta-analysis. Acta Paediatrica, 104, 114-134.

Preventing central venous catheter-related infections

Lai, N. M., Lai, N. A., O’Riordan, E., Chaiyakunapruk, N., Taylor, J. E., & Tan, K. (2016). Skin antisepsis for reducing central venous catheter-related infections. Cochrane Database of Systematic Reviews, (7), CD010140.

Chamberlain NR451 Capstone Project Paper

Increasing health insurance coverage for vulnerable populations

Jia, L., Yuan, B., Huang, F., Lu, Y., Garner, P., & Meng, Q. (2014). Strategies for expanding health insurance coverage in vulnerable populations. Cochrane Database of Systematic Reviews, (11), 1-41. CD008194. doi:10.1002/14651858.CD008194.pub3.

Chamberlain Library Permalink: http://proxy.chamberlain.edu:8080/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=mdc&AN=25425010&site=eds-live&scope=site

Preventing teen pregnancy and sexually-transmitted disease

Mason-Jones, A. J., Sinclair, D., Mathews, C., Kagee, A., Hillman, A., & Lombard, C. (2016). School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents. Cochrane Database of Systematic Reviews, (11), CD006417. doi:10.1002/14651858.CD006417.pub3.

Chamberlain Library Permalink: http://proxy.chamberlain.edu:8080/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=mdc&AN=27824221&site=eds-live&scope=site

Reducing hospital readmissions

Mistiaen, P., & Poot, E. (2006). Telephone follow-up, initiated by a hospital-based health professional, for post discharge problems in patients discharged from hospital to home. Cochrane Consumers and Communication Group. (4), CD004510. doi:10.1002/14651858.CD004510.pub3.

Chamberlain Library Permalink: http://onlinelibrary.wiley.com.proxy.chamberlain.edu:8080/doi/10.1002/14651858.CD004510.pub3/full

Capstone Project Milestone 1: Practice Issue and Evidence Summary Worksheets

Student Name:                                                          Date:

Directions

  1. Refer to the guidelines for specific details on how to complete this assignment.
  2. Type your answers directly into the worksheets below.
  3. Submit to the Dropbox by the end of Week 3, Sunday at 11:59 p.m. MT.
  4. Post questions about this assignment to the Q & A Forum. You may also email questions to the instructor for a private response.
  5. Chamberlain NR451 Capstone Project Paper

Practice Issue Worksheet

What is the Practice Issue? 

 

Define the scope of the Practice Issue: What is the practice area?___ Clinical

___ Education

___ Administration

___ Other (list)_________________________________

How was the practice issue identified? (check all that apply)___ Safety/risk management concerns

___ Unsatisfactory patient outcomes

___ Wide variations in practice

___ Significant financial concerns

___ Difference between hospital and community practice

___ Clinical practice issue is a concern

___ Procedure or process is a time waster

___ Clinical practice issue has no scientific base

__ Other:

Describe the rationale for your checked selections:What evidence must be gathered? (check all that apply)___ Literature search___ Guidelines

___ Expert Opinion

___ Patient Preferences

___ Clinical Expertise___ Financial Analysis

___ Standards (Regulatory, professional, community)

___ Other

Describe the rationale for your checked selections:

Chamberlain NR451 Capstone Project Paper

Evidence Summary Worksheet

Directions: Please type your answers directly into the worksheet.

Describe the practice problem in your own words with reference to the identified population, setting and magnitude of the problem in measurable terms:Find a source of evidence that is a systematic review article on a nursing topic that is relevant to your practice problem. Write the complete APA reference for the systematic review article you selected:

Define the search terms for your systematic review:

Identify the objectives of the article.

Provide a statement of the questions being addressed in the work and how they relate to your practice issue:

Summarize (in your own words) the interventions the author(s) suggest to improve patient outcomes.

Summarize the main findings by the authors of your systematic review including the strength of evidence for each main outcome.  Consider the relevance to your project proposal for the Milestone 2 project paper.

Outline evidence-based solutions that you will consider for your project.

Discuss any limitations to the studies performed that you believe impacts your ability to utilize the research in your project.

iCARE Paper